Seed Grants


One major focus of the P30 Enrichment Program funding is to provide pilot and feasibility (P&F), or seed grants, for new collaborative research projects. A fundamental requirement for all P&F seed grants is a focus on skin biology and disease in accordance with NIAMS mission. Also, to promote the entry of junior scientists to NIAMS research, the program favors applications where at least one of the PIs is an assistant professor, although this is not a requirement. In addition, the seed grant program uses different strategies to promote the overall goal of the Center, such as funding collaborative grants between skin biologists and experts in at least one of the Core areas, or between skin biologists and scientists from other areas of biology, engineering, chemistry and other disciplines that explore novel types of multidisciplinary projects. All P&F projects are expected to use at least one of our Resource Cores.


The program is not currently accepting applications.

Donor Opportunities

Seed grants are an outstanding opportunity for donors to really make an impact on scientific progress. The UC Irvine Stem Cell Research Center (SCRC), which manages the P30 NIAMS award and assists with its administration, also has a successful seed grant program. The SCRC has funded 13 projects for $454,000 over the past 5 years. In turn, these projects have been awarded over $11.3 million in additional external funding, demonstrating the effectiveness of such programs in over 25-fold return on investment.


Mechanochemical regulation of cell-cell communication during wound healing in the skin
Wendy Liu, Max Plikus, Qing Nie

Live cell mapping of Rac1/RhoA signal transduction dynamics during epidermal wound healing and partial Epithelial-to-Mesenchymal Transition
Michelle Digman, Xing Dai, Rachel Cinco

A key role for FAAH-regulated N-acyltaurine (NAT) signaling in diabetic wound healing
Danielle Piomelli, Max Plikus

Exploring the mechanistic links between skin and whole-body physiology
Selma Masri, Xing Dai

Interactions between skin and the immune system in skin health and disease
Francesco Marangoni, Xing Dai

Illuminating tissue-wide, spatiotemporal transcriptome and proteome landscapes in skin development and cancer
Weian Zhao, Scott Atwood

Blastema-independent mechanism for skin regeneration in salamanders
Max Plikus, David Gardiner

Piezo1 dynamics in keratinocyte migration during skin wound healing
Medha Pathak, John Lowengrub

Control Mechanisms of Hair Follicle Growth Regression
Qixuan Wang, Qing Nie, Max Plikus

Defining aging-induced metabolic alterations in skin would healing
Cholsoon Jang, Xing Dai

Defining keratinocyte metabolic changes in stable vitiligo treatment response
Jessica Shiu, Anand Ganesan, Mihaela Balu

Spatial and temporal monitoring of keratinocyte cell states in living 3D human skin organoids by multidimensional microscopy phenotyping
Lorenzo Scipioni, Scott Atwood, Michelle Digman, Enrico Gratton

Identification and characterization of microproteins promoting DNA repair in skin cells
Remi Buisson

Single-cell transcriptomics of vulvar lichen sclerosus (LS)
Christina Kraus, Xing Dai

Characterize Fibroblast-specific YAP/TAZ Function in Skin Wounding
Xing Dai, Maksim Plikus

Compare conventional melanocytes and melanocyte-like cells to characterize their expression of key immune transcripts using computer programming analysis
Qing Nie, Julie Wiedemann